Mammalian Cell Line Development Services

Mammalian Cell Line Development

Product Titers Up to 10 g/L

High-Performance Mammalian Cell Line Development

The combination of high expression host cell line, advanced vector technology, and stringency of selection directly impacts development speed, manufacturing efficiency, and product consistency. Cytovance’s mammalian cell line development platform generates stable, high-producing CHO cell lines engineered to support the successful advancement of complex biologics. Leveraging proven expression technologies and a rigorous clone selection strategy, our cell line development services deliver high-yield cell lines with titers reaching up to 10 g/L for monoclonal antibodies, enabling efficient process development and scalable manufacturing.

Stable CHO Cell Lines Designed for Biologics Success

Speed, Quality, and Scalability

Our CHO cell line development approach combines advanced screening methodologies with data-driven selection criteria to identify clones with the productivity, stability, and product quality attributes required for long-term success. By evaluating critical performance characteristics early, we help accelerate biologics development timelines, improve manufacturing economics and reduce risk during scale-up and commercialization.

A Seamless Path from Cell Line to Commercial Manufacturing

Integrated Development and Manufacturing

With more than 20 years in mammalian-based protein production, our experience and culture of ingenuity offer significant benefits to therapeutic developers. Our scientists work collaboratively across cell line development, upstream process development, analytical characterization, and manufacturing to establish a strong foundation for scale-up. This integrated strategy promotes continuity, helps streamline development, enhances process understanding, and supports a smoother path toward clinical and commercial production.

Related Areas of Expertise

Mammalian Process Development

Take your productivity to the next level with our process development experts.

Mammalian Analytical Development

Robust analytical method development or transfer personalized for your mammalian-derived biologic.

Mammalian Manufacturing

Benefit from our full-service CGMP facility from cell banks to production with up to 2,000L capacity.